AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

01 Dec - 08 Dec	Air Europa
02 Dec - 09 Dec	KLM
19 Dec - 26 Dec	Royal Air Maroc
23 Dec - 04 Jan	Air Europa
15 Dec - 23 Dec	Air Europa
15 Dec - 21 Dec	Air Europa
18 Dec - 29 Dec	Qatar Airways
26 Dec - 02 Jan	Air Europa
20 Dec - 03 Jan	Air Europa
25 Dec - 03 Jan	Air Europa
01 Dec - 08 Dec	Turkish Airlines	direct
19 Dec - 26 Dec	Turkish Airlines	direct
18 Dec - 29 Dec	Turkish Airlines	direct
23 Dec - 04 Jan	Turkish Airlines	direct
15 Dec - 21 Dec	Turkish Airlines	direct
19 Dec - 03 Jan	Turkish Airlines	direct
20 Dec - 03 Jan	Turkish Airlines	direct
25 Dec - 03 Jan	Turkish Airlines	direct
26 Dec - 02 Jan	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Sao Paulo in December from $841

Return flights