AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

01 Dec - 05 Dec	KLM
04 Dec - 14 Dec	Air France
26 Dec - 24 Jan	British Airways
01 Dec - 16 Dec	Air Europa
30 Dec - 20 Jan	Air Europa
01 Dec - 31 Dec	Air Europa
01 Dec - 19 Jan	KLM
10 Dec - 24 Dec	British Airways
26 Dec - 11 Jan	Qatar Airways
10 Dec - 17 Dec	Air Europa
21 Dec - 25 Jan	Air Europa
23 Dec - 04 Jan	Qatar Airways
20 Dec - 05 Jan	Qatar Airways
23 Dec - 30 Dec	Qatar Airways
20 Dec - 04 Jan	Qatar Airways
23 Dec - 30 Dec	Turkish Airlines	direct
01 Dec - 16 Dec	Turkish Airlines	direct
18 Dec - 28 Dec	Qatar Airways
26 Dec - 11 Jan	Turkish Airlines	direct
30 Dec - 20 Jan	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Sao Paulo

Cheap car rent in Sao Paulo

Cheapest return flights from Istanbul to Sao Paulo in December from $807

Return flights