Cheapest return flights from Istanbul to Madrid in December from $164

AirHint found the following cheapest return flights from Istanbul (IST) to Madrid (MAD) in December 2025 (see full year).

Return flights

02 Dec - 09 Dec Wizz Air UK
08 Dec - 12 Dec Aegean Airlines
14 Dec - 18 Dec SKY express
02 Dec - 09 Dec Pegasus Airlines direct
18 Dec - 16 Jan Pegasus Airlines
05 Dec - 08 Dec Pegasus Airlines
12 Dec - 16 Dec Pegasus Airlines
16 Dec - 23 Dec Pegasus Airlines
17 Dec - 24 Dec Pegasus Airlines
06 Dec - 10 Dec AJet
06 Dec - 08 Dec Wizz Air UK
18 Dec - 16 Jan Pegasus Airlines direct
31 Dec - 12 Jan Aegean Airlines
30 Dec - 03 Jan AJet
30 Dec - 01 Jan Aegean Airlines
29 Dec - 02 Jan Aegean Airlines
29 Dec - 03 Jan Aegean Airlines
14 Dec - 01 Jan SKY express
31 Dec - 12 Jan Pegasus Airlines direct
28 Dec - 18 Jan SKY express

Also check the deals for one-way flights from Istanbul to Madrid in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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