Cheapest return flights from Madrid to Istanbul in October from $211

Best time to book flights for Madrid (MAD) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in October 2025 (see full year).

Return flights

12 Oct - 16 Oct Wizz Air Malta
07 Oct - 15 Oct Iberia Express
15 Oct - 21 Oct Wizz Air
08 Oct - 15 Oct Iberia
18 Oct - 21 Oct Wizz Air Malta
20 Oct - 12 Nov easyJet
30 Oct - 04 Nov Pegasus Airlines direct
11 Oct - 15 Oct Wizz Air Malta
08 Oct - 14 Oct Iberia
15 Oct - 22 Oct Wizz Air
01 Oct - 10 Oct Wizz Air Malta
08 Oct - 12 Oct Wizz Air Malta
30 Oct - 11 Nov Aegean Airlines
31 Oct - 04 Nov SunExpress
24 Oct - 04 Nov Pegasus Airlines direct
30 Oct - 05 Nov Aegean Airlines
30 Oct - 05 Nov Pegasus Airlines direct
22 Oct - 01 Nov easyJet
30 Oct - 11 Nov Pegasus Airlines direct
29 Oct - 03 Nov ITA Airways

Also check the deals for one-way flights from Madrid to Istanbul in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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