Cheapest return flights from Madrid to Istanbul in December from $171

AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in December 2025 (see full year).

Return flights

04 Dec - 11 Dec Air Europa
10 Dec - 14 Dec SKY express
08 Dec - 14 Dec SKY express
07 Dec - 14 Dec SKY express
03 Dec - 14 Dec SKY express
11 Dec - 14 Dec SKY express
01 Dec - 14 Dec SKY express
05 Dec - 10 Dec SKY express
10 Dec - 16 Dec Pegasus Airlines direct
01 Dec - 12 Dec SKY express
28 Dec - 09 Jan Aegean Airlines
28 Dec - 08 Jan Aegean Airlines
15 Dec - 05 Jan SKY express
25 Dec - 02 Jan Aegean Airlines
21 Dec - 05 Jan Aegean Airlines
29 Dec - 09 Jan Aegean Airlines
30 Dec - 31 Jan Iberia Express
31 Dec - 07 Jan Aegean Airlines
22 Dec - 02 Jan Aegean Airlines
20 Dec - 10 Jan Aegean Airlines

Also check the deals for one-way flights from Madrid to Istanbul in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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