Cheapest return flights from Madrid to Istanbul in December from $170

Best time to book flights for Madrid (MAD) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in December 2025 (see full year).

Return flights

03 Dec - 10 Dec Pegasus Airlines direct
02 Dec - 09 Dec Pegasus Airlines direct
11 Dec - 18 Dec Wizz Air Malta
05 Dec - 13 Dec easyJet
09 Dec - 14 Dec Pegasus Airlines direct
05 Dec - 10 Dec Pegasus Airlines direct
03 Dec - 07 Dec Pegasus Airlines
01 Dec - 05 Dec Iberia Express
01 Dec - 07 Dec Iberia Express
01 Dec - 12 Dec Iberia Express
30 Dec - 10 Jan Wizz Air
28 Dec - 15 Jan easyJet
31 Dec - 10 Jan Aegean Airlines
28 Dec - 16 Jan easyJet
30 Dec - 03 Jan Iberia Express
28 Dec - 05 Jan Iberia
31 Dec - 06 Jan Aegean Airlines
29 Dec - 04 Jan Aegean Airlines
26 Dec - 02 Jan Aegean Airlines
25 Dec - 01 Jan Aegean Airlines

Also check the deals for one-way flights from Madrid to Istanbul in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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