Cheapest return flights from Madrid to Istanbul in May from $190

Best time to book flights for Madrid (MAD) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in May 2025 (see full year).

Return flights

17 May - 21 May Air Europa
27 May - 02 Jun Air Europa
23 May - 03 Jun Air Europa
20 May - 30 May Wizz Air
17 May - 17 Jun Iberia
22 May - 29 May Air Europa
28 May - 03 Jun Wizz Air Malta
13 May - 21 May Ryanair
27 May - 03 Jun Wizz Air
27 May - 11 Jun Wizz Air
21 May - 27 May Air Europa
17 May - 20 May Air Europa
27 May - 30 May Wizz Air
27 May - 01 Jun Wizz Air
17 May - 27 May Air Europa
28 May - 02 Jun Wizz Air
13 May - 20 May Ryanair
29 May - 10 Jun Iberia Express
29 May - 02 Jun Iberia Express
17 May - 19 May Wizz Air

Also check the deals for one-way flights from Madrid to Istanbul in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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