Cheapest return flights from Madrid to Istanbul in September from $153

AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in September 2025 (see full year).

Return flights

10 Sep - 16 Sep Pegasus Airlines direct
09 Sep - 12 Sep Wizz Air
16 Sep - 20 Sep Wizz Air Malta
16 Sep - 23 Sep Wizz Air Malta
23 Sep - 30 Sep Wizz Air Malta
24 Sep - 29 Sep Wizz Air Malta
16 Sep - 22 Sep Wizz Air Malta
16 Sep - 30 Sep Wizz Air Malta
12 Sep - 15 Sep Pegasus Airlines
25 Sep - 30 Sep Wizz Air Malta
23 Sep - 02 Oct Wizz Air Malta
25 Sep - 05 Oct Wizz Air Malta
10 Sep - 07 Oct Ryanair
30 Sep - 05 Oct Wizz Air Malta
30 Sep - 06 Oct Wizz Air Malta
26 Sep - 13 Oct easyJet
23 Sep - 01 Oct Wizz Air Malta
30 Sep - 07 Oct Wizz Air Malta
30 Sep - 09 Oct Wizz Air Malta
03 Sep - 02 Oct Wizz Air

Also check the deals for one-way flights from Madrid to Istanbul in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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