Cheapest return flights from Madrid to Panama City in November from $654

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in November 2025 (see full year).

Return flights

13 Nov - 18 Nov Avianca
14 Nov - 19 Nov Air France
21 Nov - 30 Nov Air France
14 Nov - 23 Nov Air France
13 Nov - 25 Nov Air France
08 Nov - 02 Dec Air Europa direct
14 Nov - 19 Nov Air Europa direct
07 Nov - 16 Nov Air Europa direct
07 Nov - 15 Nov Air Europa direct
21 Nov - 30 Nov Air Europa direct
16 Nov - 26 Nov Air Europa direct
21 Nov - 06 Dec Air Europa direct
22 Nov - 06 Dec Air Europa direct
28 Nov - 07 Dec Air Europa direct
28 Nov - 08 Dec Air Europa direct
25 Nov - 05 Dec Air Europa direct
29 Nov - 08 Dec Iberia direct
29 Nov - 07 Dec Air Europa direct
27 Nov - 07 Dec United
27 Nov - 08 Dec United

Also check the deals for one-way flights from Madrid to Panama City in November.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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