Cheapest return flights from Madrid to Panama City in November from $690

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in November 2025 (see full year).

Return flights

15 Nov - 22 Nov Air Europa direct
14 Nov - 28 Nov Air Europa direct
15 Nov - 23 Nov Air Europa direct
15 Nov - 28 Nov Air Europa direct
15 Nov - 29 Nov Air Europa direct
01 Nov - 19 Nov Air Europa direct
01 Nov - 26 Nov Air Europa direct
01 Nov - 15 Nov Air Europa direct
01 Nov - 10 Nov Air Europa direct
17 Nov - 28 Nov KLM
29 Nov - 11 Dec Air France
29 Nov - 13 Dec Air France
29 Nov - 11 Dec Air Europa direct
29 Nov - 13 Dec Iberia direct
30 Nov - 13 Dec KLM
28 Nov - 14 Dec Air France
28 Nov - 08 Dec Air France

Also check the deals for one-way flights from Madrid to Panama City in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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