Cheapest return flights from Madrid to Panama City in April from $625

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in April 2026 (see full year).

Return flights

24 Apr - 02 May Avianca
26 Apr - 03 May Avianca
15 Apr - 22 Apr Avianca
02 Apr - 09 Apr Iberia direct
02 Apr - 11 Apr Iberia direct
07 Apr - 21 Apr Iberia direct
15 Apr - 22 Apr Air Europa direct
11 Apr - 18 Apr Air Europa direct
03 Apr - 10 Apr United
03 Apr - 10 Apr Air Europa direct

Also check the deals for one-way flights from Madrid to Panama City in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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