Cheapest return flights from Madrid to Santiago in December from $963

Best time to book flights for Madrid (MAD) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in December 2025 (see full year).

Return flights

13 Dec - 07 Jan Air Canada
12 Dec - 07 Jan Air Canada
01 Dec - 09 Dec TAP
30 Dec - 28 Jan Lufthansa
31 Dec - 15 Jan Delta
01 Dec - 11 Dec Iberia
10 Dec - 31 Dec LATAM Airlines Group
01 Dec - 11 Dec Iberia direct
01 Dec - 15 Dec LATAM Airlines Group
01 Dec - 09 Dec Iberia direct
01 Dec - 13 Dec LATAM Airlines Group
30 Dec - 28 Jan LATAM Airlines Group direct
31 Dec - 25 Jan LATAM Airlines Group
31 Dec - 23 Jan LATAM Airlines Group
05 Dec - 12 Dec easyJet
24 Dec - 23 Jan TAP
05 Dec - 18 Dec LATAM Airlines Group
02 Dec - 16 Dec LATAM Airlines Group
13 Dec - 18 Jan Air Europa
31 Dec - 29 Jan LATAM Airlines Group

Also check the deals for one-way flights from Madrid to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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