Cheapest return flights from Madrid to Santa Cruz in October from $1080

Best time to book flights for Madrid (MAD) to Santa Cruz (VVI) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Santa Cruz (VVI) in October 2025 (see full year).

Return flights

20 Oct - 03 Nov LATAM Airlines Group
01 Oct - 28 Oct Air Europa direct
03 Oct - 18 Oct Avianca
10 Oct - 01 Nov Avianca
10 Oct - 01 Nov Iberia direct
12 Oct - 28 Oct Air Europa
12 Oct - 28 Oct Iberia direct
13 Oct - 27 Oct LATAM Airlines Group
10 Oct - 17 Oct LATAM Airlines Group
13 Oct - 20 Oct LATAM Airlines Group
13 Oct - 29 Oct LATAM Airlines Group
22 Oct - 22 Nov LATAM Airlines Group
01 Oct - 29 Oct LATAM Airlines Group
10 Oct - 29 Nov LATAM Airlines Group
15 Oct - 25 Oct Avianca
18 Oct - 01 Nov Iberia
31 Oct - 15 Nov Air Europa direct
07 Oct - 29 Nov TAP
17 Oct - 02 Nov LATAM Airlines Group

Also check the deals for one-way flights from Madrid to Santa Cruz in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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