Cheapest return flights from Chicago to Santiago in December from $591

AirHint found the following cheapest return flights from Chicago (ORD) to Santiago (SCL) in December 2025 (see full year).

Return flights

02 Dec - 16 Dec Spirit Airlines
02 Dec - 18 Dec Spirit Airlines
12 Dec - 11 Jan Spirit Airlines
14 Dec - 28 Dec Spirit Airlines
24 Dec - 05 Jan Spirit Airlines
20 Dec - 27 Dec Frontier Airlines
26 Dec - 04 Jan Frontier Airlines
22 Dec - 31 Dec American Airlines

Also check the deals for one-way flights from Chicago to Santiago in December.

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