Cheapest return flights from Panama City to Madrid in October from $707

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in October 2025 (see full year).

Return flights

30 Oct - 13 Nov Avianca
31 Oct - 11 Nov Avianca
24 Oct - 11 Nov Avianca
31 Oct - 16 Nov Avianca
31 Oct - 17 Nov Avianca
30 Oct - 08 Nov Avianca
30 Oct - 09 Nov Avianca
28 Oct - 11 Nov Avianca
29 Oct - 12 Nov Avianca
30 Oct - 20 Nov Avianca
24 Oct - 30 Oct Avianca
25 Oct - 29 Oct Iberia
24 Oct - 26 Oct Avianca
25 Oct - 29 Oct Iberia direct
24 Oct - 30 Oct Air Europa direct
24 Oct - 31 Oct Air Europa direct
24 Oct - 26 Oct Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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