Cheapest return flights from Panama City to Madrid in December from $926

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in December 2026 (see full year).

Return flights

01 Dec - 31 Dec Air France
21 Dec - 12 Jan KLM
22 Dec - 13 Jan KLM
10 Dec - 20 Dec Turkish Airlines
19 Dec - 08 Jan Air France
10 Dec - 20 Dec Air Europa direct
21 Dec - 12 Jan Air Europa direct
22 Dec - 13 Jan Air Europa direct
01 Dec - 18 Dec Air France
19 Dec - 08 Jan Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in December.

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