Cheapest return flights from Panama City to Madrid in April from $683

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in April 2026 (see full year).

Return flights

17 Apr - 02 May Air France
21 Apr - 28 Apr Air Europa direct
19 Apr - 03 May Air Europa direct
19 Apr - 02 May Air Europa direct
16 Apr - 24 Apr Air Europa direct
16 Apr - 30 Apr Air Europa direct
17 Apr - 02 May Air Europa direct
06 Apr - 13 Apr Air Europa direct
03 Apr - 18 Apr Air Europa direct
04 Apr - 18 Apr Air Europa direct
11 Apr - 24 Apr Air Europa direct
23 Apr - 23 May Air France
17 Apr - 03 May Copa
20 Apr - 25 Apr Air Europa direct
23 Apr - 23 May Copa direct

Also check the deals for one-way flights from Panama City to Madrid in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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