Cheapest return flights from Panama City to Madrid in April from $625

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in April 2026 (see full year).

Return flights

20 Apr - 04 May Air Europa direct
20 Apr - 29 Apr Air Europa direct
15 Apr - 05 May Air Europa direct
24 Apr - 10 May Air Europa direct
19 Apr - 08 May Air Europa direct
28 Apr - 06 May Air Europa direct
16 Apr - 19 May Air France
26 Apr - 17 May Air France
26 Apr - 03 May Air France
22 Apr - 02 May Air France
13 Apr - 21 Apr Air France
14 Apr - 19 May Air France
15 Apr - 26 Apr Iberia direct
08 Apr - 17 Apr Iberia direct
16 Apr - 28 Apr Air Europa direct
15 Apr - 25 Apr Air Europa direct
25 Apr - 27 Apr Air Europa direct
20 Apr - 25 Apr Air Europa direct
14 Apr - 22 Apr Air Europa direct
01 Apr - 15 Apr Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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