Cheapest return flights from Panama City to Madrid in September from $725

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in September 2026 (see full year).

Return flights

25 Sep - 09 Oct Air Europa direct
23 Sep - 27 Sep Iberia direct
20 Sep - 10 Oct Air Europa direct
11 Sep - 18 Sep Air France
11 Sep - 26 Sep Air France
11 Sep - 18 Sep Iberia direct
16 Sep - 03 Oct Air Europa direct
15 Sep - 30 Sep Air Europa direct
01 Sep - 15 Sep Air Europa direct
11 Sep - 26 Sep Air Europa direct
01 Sep - 25 Sep Air France

Also check the deals for one-way flights from Panama City to Madrid in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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