Cheapest return flights from Santiago to La Serena in September from $54

AirHint found the following cheapest return flights from Santiago (SCL) to La Serena (LSC) in September 2025 (see full year).

Return flights

05 Sep - 17 Sep JetSmart direct
05 Sep - 14 Sep JetSmart direct
14 Sep - 17 Sep JetSmart direct
16 Sep - 17 Sep JetSmart direct
11 Sep - 17 Sep JetSmart direct
11 Sep - 14 Sep JetSmart direct
11 Sep - 18 Sep LATAM Airlines Group direct
14 Sep - 05 Oct LATAM Airlines Group direct
12 Sep - 17 Sep JetSmart direct
12 Sep - 14 Sep JetSmart direct
06 Sep - 17 Sep JetSmart direct
26 Sep - 10 Oct JetSmart direct
19 Sep - 10 Oct JetSmart direct
25 Sep - 10 Oct JetSmart direct
22 Sep - 10 Oct JetSmart direct
27 Sep - 10 Oct JetSmart direct
28 Sep - 10 Oct JetSmart direct
27 Sep - 23 Oct Sky Airline direct
25 Sep - 05 Oct JetSmart direct
22 Sep - 05 Oct JetSmart direct

Also check the deals for one-way flights from Santiago to La Serena in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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