Cheapest return flights from Santiago to La Serena in September from $51

AirHint found the following cheapest return flights from Santiago (SCL) to La Serena (LSC) in September 2025 (see full year).

Return flights

27 Sep - 28 Sep LATAM Airlines Group direct
24 Sep - 26 Sep LATAM Airlines Group direct
23 Sep - 30 Sep LATAM Airlines Group direct
28 Sep - 05 Oct LATAM Airlines Group direct
20 Sep - 27 Sep LATAM Airlines Group direct
23 Sep - 26 Sep LATAM Airlines Group direct
24 Sep - 25 Sep LATAM Airlines Group direct
29 Sep - 30 Sep Sky Airline direct
22 Sep - 25 Sep Sky Airline direct
28 Sep - 07 Oct JetSmart direct
28 Sep - 16 Oct JetSmart direct
27 Sep - 07 Oct JetSmart direct
27 Sep - 16 Oct JetSmart direct
20 Sep - 07 Oct JetSmart direct
20 Sep - 25 Sep JetSmart direct
20 Sep - 26 Sep JetSmart direct
28 Sep - 04 Oct JetSmart direct
28 Sep - 10 Oct JetSmart direct
28 Sep - 02 Oct JetSmart direct
27 Sep - 04 Oct JetSmart direct

Also check the deals for one-way flights from Santiago to La Serena in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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