AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

Return flights

14 Dec - 17 Jan	WORLD2FLY	direct
14 Dec - 21 Jan	WORLD2FLY
20 Dec - 18 Jan	WORLD2FLY	direct
27 Dec - 15 Jan	WORLD2FLY	direct
21 Dec - 15 Jan	WORLD2FLY	direct
16 Dec - 15 Jan	Air Europa	direct
11 Dec - 15 Dec	WORLD2FLY
14 Dec - 21 Jan	Iberia	direct
10 Dec - 06 Jan	Iberia	direct
13 Dec - 07 Jan	WORLD2FLY	direct
21 Dec - 06 Jan	WORLD2FLY	direct
24 Dec - 31 Dec	Air Europa	direct
23 Dec - 31 Dec	Air Europa	direct
07 Dec - 15 Dec	WORLD2FLY
11 Dec - 24 Dec	WORLD2FLY
23 Dec - 30 Dec	Iberia
21 Dec - 27 Dec	WORLD2FLY
22 Dec - 29 Dec	Iberia
08 Dec - 15 Dec	Air Europa
15 Dec - 25 Dec	Iberia

Also check the deals for one-way flights from Santo Domingo to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santo Domingo to Madrid in December from $746

Return flights