AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

Return flights

20 Dec - 03 Jan	Air Europa	direct
20 Dec - 28 Jan	Air Europa	direct
18 Dec - 03 Jan	Air Europa	direct
13 Dec - 07 Jan	WORLD2FLY	direct
04 Dec - 06 Jan	Air Europa	direct
10 Dec - 06 Jan	Air Europa	direct
20 Dec - 08 Jan	WORLD2FLY	direct
02 Dec - 04 Dec	Spirit Airlines
20 Dec - 11 Jan	WORLD2FLY	direct
18 Dec - 21 Jan	WORLD2FLY
15 Dec - 15 Jan	Air Europa	direct
24 Dec - 31 Dec	Iberia	direct
09 Dec - 31 Dec	Iberia	direct
05 Dec - 12 Dec	jetBlue
18 Dec - 28 Dec	WORLD2FLY
18 Dec - 29 Dec	WORLD2FLY
18 Dec - 28 Dec	WORLD2FLY	direct
18 Dec - 21 Dec	WORLD2FLY
20 Dec - 25 Dec	WORLD2FLY	direct
20 Dec - 27 Dec	Iberia

Also check the deals for one-way flights from Santo Domingo to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Cheapest return flights from Santo Domingo to Madrid in December from $628

Return flights