AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

Return flights

13 Dec - 01 Jan	WORLD2FLY	direct
20 Dec - 03 Jan	WORLD2FLY	direct
13 Dec - 28 Jan	Iberia	direct
18 Dec - 03 Jan	WORLD2FLY	direct
21 Dec - 01 Jan	WORLD2FLY	direct
20 Dec - 08 Jan	WORLD2FLY	direct
20 Dec - 04 Jan	WORLD2FLY	direct
27 Dec - 11 Jan	WORLD2FLY	direct
19 Dec - 06 Jan	Air Europa	direct
22 Dec - 02 Jan	Iberia	direct
18 Dec - 27 Dec	Air Europa	direct
19 Dec - 27 Dec	Air Europa	direct
18 Dec - 28 Dec	Air Europa	direct
22 Dec - 29 Dec	Iberia
22 Dec - 29 Dec	Air Europa	direct
02 Dec - 21 Dec	KLM
02 Dec - 21 Dec	Air Europa	direct

Also check the deals for one-way flights from Santo Domingo to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santo Domingo to Madrid in December from $748

Return flights