Cheapest return flights from Tampa to Panama City in December from $435

AirHint found the following cheapest return flights from Tampa (TPA) to Panama City (PTY) in December 2025 (see full year).

Return flights

30 Dec - 08 Jan Copa direct
30 Dec - 06 Jan Spirit Airlines
27 Dec - 03 Jan Avianca
27 Dec - 03 Jan Copa direct
30 Dec - 06 Jan Copa direct
20 Dec - 02 Jan Avianca
19 Dec - 03 Jan Allegiant Air
19 Dec - 03 Jan Copa direct
20 Dec - 02 Jan Copa direct

Also check the deals for one-way flights from Tampa to Panama City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Feel free to contact us with any feedback or request another flight research.